Certified Clinical Hemodialysis Technician (CCHT) Practice Exam

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What does the Three-pore Model (TPM) describe?

Vascular resistance in the kidney

Sodium and water removal across the peritoneal membrane

The Three-pore Model (TPM) primarily describes the process of sodium and water removal across the peritoneal membrane during peritoneal dialysis. This model helps to elucidate how solutes and fluids move through the dialysis membrane, taking into account the size and charge of different molecules. It distinguishes between three types of pores within the membrane—small, medium, and large—that interact differently with solutes based on their size and chemical properties.

In this context, the model demonstrates how the movement of sodium and water can be optimized during the dialysis process, which is crucial for patients who rely on peritoneal dialysis to manage their renal function. This understanding is essential for dialysate formulation and treatment planning to ensure effective removal of excess fluid and electrolytes from the body, helping to maintain homeostasis in patients with kidney failure.

The other options, while relevant to renal physiology, do not capture the specific mechanism described by the Three-pore Model. Vascular resistance in the kidney relates to blood flow dynamics, protein leakage refers to glomerular filtration issues, and electrolyte balance pertains to broader physiological processes not specifically outlined in the Three-pore Model.

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Protein leakage in glomerular filtration

Electrolyte balance in the blood

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